Prices last checked October 29, 2026
Domino's pepperoni pizza prices by size and calories per slice.
Pepperoni is Domino’s most popular topping. A large Hand Tossed pepperoni pizza costs about $16.99 at menu price, but it is the pizza most often covered by deals: at most stores a 1-topping pizza is $7.99 for carryout, and two or more large 2-topping pizzas are about $11.99 each.
A large slice has 295 calories, only about 10 more than a cheese slice, because Domino’s uses less cheese when a pizza has toppings.
Pepperoni Pizza Price (October 2026)
| Item | Typical price | Calories |
|---|---|---|
| Pepperoni Pizza (Small (10-inch)) | $11.74 | 1,200 |
| Pepperoni Pizza (Medium (12-inch)) | $14.49 | 1,680 |
| Pepperoni Pizza (Large (14-inch)) | $16.99 | 2,360 |
| Pepperoni Pizza (X-Large (16-inch)) | $19.24 | 2,760 |
Pepperoni Pizza Calories and Nutrition
The Pepperoni Pizza has 295 calories, about 15% of a 2,000-calorie day, along with 11 g of protein and 665 mg of sodium.
| Nutrient | Amount | % Daily Value* |
|---|---|---|
| Calories | 295 | 15% |
| Total fat | 12 g | 15% |
| Carbohydrates | 33 g | 12% |
| Protein | 11 g | 22% |
| Sodium | 665 mg | 29% |
*Percent Daily Values are based on a 2,000-calorie diet. Nutrition is for one large Hand Tossed slice (1/8 of the pizza), added up from Domino's official values. Prices are the cheese pizza price plus a typical one-topping charge. Nutrition is approximate and based on Domino's published U.S. nutrition information.
What's in the Pepperoni Pizza?
- Crust of your choice
- Robust tomato sauce
- Mozzarella
- Pepperoni
Allergens: Domino's lists allergens for the Pepperoni Pizza in its online Allergen & Ingredient Guide. Most Domino's pizzas, breads, pasta and sandwiches contain wheat and milk, and some toppings and sauces contain soy or egg. Recipes and suppliers can change, so always check Domino's allergen information or ask your server if you have a food allergy.
When can you order the Pepperoni Pizza?
The Pepperoni Pizza is available for delivery and carryout whenever your store is open, usually from 10 or 10:30 a.m. until midnight or later. Specialty pizzas come on any crust that is offered in the size you choose; the prices here are for Hand Tossed, and the X-Large is New York Style at most stores. See Domino's hours.
Is the Pepperoni Pizza worth it?
At a typical $16.99, the Pepperoni Pizza works out to about $5.76 per 100 calories and 0.6 grams of protein per dollar, about average for build your own pizza & crusts on the menu.
Comparing sizes, the x-large (16-inch) gives you the most food for your money at roughly $0.70 per 100 calories.
On a tighter budget? The Gluten Free Crust costs about $12.99.
Ordering tips
- Never pay menu price: the $7.99 carryout deal or a 2-topping deal is almost always cheaper.
- Want more pepperoni? The Ultimate Pepperoni has two layers.
Pepperoni Pizza FAQ
How much does the Pepperoni Pizza cost at Domino's?
At a typical U.S. Domino's in October 2026, the Pepperoni Pizza costs: Small (10-inch) $11.74, Medium (12-inch) $14.49, Large (14-inch) $16.99, X-Large (16-inch) $19.24.
How many calories are in the Pepperoni Pizza?
The Pepperoni Pizza has 295 calories, 12 g of fat, 33 g of carbohydrates and 11 g of protein. Nutrition is for one large Hand Tossed slice (1/8 of the pizza), added up from Domino's official values. Prices are the cheese pizza price plus a typical one-topping charge.
What crust can you get the Pepperoni Pizza on?
Small: Hand Tossed or Gluten Free (Crunchy Thin at some stores). Medium: Hand Tossed, Crunchy Thin, New York Style, Handmade Pan or Parmesan Stuffed Crust. Large: Hand Tossed, Crunchy Thin or New York Style. X-Large: New York Style at most stores.
How many calories are in a slice of Domino's pepperoni pizza?
A large Hand Tossed slice has about 295 calories; a medium slice about 210.